Cancer diagnostics has traditionally been performed by the morphological analysis of tumor tissue, mainly because of the molecular differences between healthy and cancerous (or pre-cancerous) cells are difficult to discern. Professor Tan Weihong led the research team used aptamer- refers to bind proteins or other small molecules are single-stranded or double-stranded oligonucleotides, identification of leukemia cells and normal human bone marrow cells, which for the diagnosis of cancer at the molecular level raised important breakthrough.
Aptamer refers to a protein capable of binding to small molecules, or other single-stranded or double-stranded oligonucleotides. The development of in vitro screening and PCR technology makes research Aptamer has made substantial progress in recent years, a large number of screened with a variety of specific proteins or small molecules tightly bound nucleic acid molecules (Aptamer). These Aptamer contain RNA, double-stranded DNA, single-stranded DNA oligonucleotides and other forms, the different nature of the ligand. Aptamer vitro screening not only enhances Human ferritin ELISA Kit http://www.cusabio.com/ELISA_Kit-78429/ of nucleic acid-protein interactions, but also provides a way to find new drugs.
In this experiment A successful design can identify cells mixed with normal bone marrow leukemic cells aptamers. Such aptamers can distinguish B cells and lymphoid leukemia T cells, these results imply aptamer method can be used to determine different types of cancer. Researchers hoping that probes for early cancer detection, treatment and markers, also said the technology can also play an important role in individualized treatment.